British Air Force Typhoon FGR4s have operated alongside France's air force in a combined operation targeting an hidden munitions depot in Syrian territory used by the Islamic State group (IS), per a report from the British defence ministry.
The location, pinpointed through reconnaissance, was assessed as housing weapons and explosive materials, the statement said, and was located in hills just to the north of Palmyra in central Syria.
"Our aircraft used Paveway IV guided bombs to strike a series of approach shafts providing entry to the facility... initial indications are that the objective was successfully hit," the ministry announced.
There was no sign of any civilian casualties in the operation conducted Saturday night and all the aircraft returned safely, the MoD added.
The Typhoon fighters were supported by a Voyager tanker plane.
Daesh - also known as ISIS - established militant control over significant areas in Syria and Iraq prior to its 2019 collapse.
"This strike underscores British leadership, and determination to operate in unison with our allies, to eradicate any re-emergence of the terrorist group and their violent and radical beliefs in the Middle East," Britain's Defence Chief John Healey remarked.
British military aircraft have performed patrols over Syria to "deter any attempted comeback" of IS after its routing at the Baghuz confrontation in 2019, the MoD reported.
"I extend gratitude to the personnel of our armed forces involved in this mission for their skill and their bravery," he said. "They were part of numerous British troops on duty over the holidays. This mission, to take out militants who threaten our security, shows how British military are ready to step up, continuously, protecting the UK domestically and powerful internationally."
Last December, the US military conducted what it termed a "major assault" against Daesh sites in the country, subsequent to an attack claimed the lives of two American soldiers and a civilian interpreter in the Palmyra area.
The UN reports IS still has an estimated 5,000 to 7,000 fighters in both countries.